Air oxidation increases skin irritation from fragrance terpenes.

  title={Air oxidation increases skin irritation from fragrance terpenes.},
  author={Johanna Br{\aa}red Christensson and Pia Forsstr{\"o}m and Ann-Marie Wennberg and A. -T. Karlberg and Mih{\'a}ly Matura},
  journal={Contact dermatitis},
  volume={60 1},
BACKGROUND Linalool and limonene are common fragrance terpenes that autoxidize on air exposure. The pure compounds are not allergenic but their oxidation products can cause contact allergy. Little has been investigated regarding the irritancy of oxidized terpenes. AIM The aim of this study was to investigate the irritating effect of pure and oxidized R-limonene and linalool in concentration series and to study the MNIC (Maximum Non Irritant Concentration) of autoxidized linalool and limonene… CONTINUE READING
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