Agrin is involved in lymphocytes activation that is mediated by α-dystroglycan

@inproceedings{Zhang2006AgrinII,
  title={Agrin is involved in lymphocytes activation that is mediated by α-dystroglycan},
  author={Jinping Zhang and Ying Wang and Yiwei Chu and Liping Su and Yanping Gong and Ruihua Zhang and Sidong Xiong},
  year={2006}
}
It is well established that agrin, an extracellular matrix protein, plays a crucial role in the formation of neuromuscular junctions. Recent evidence indicates that agrin also contributes to immunological synapse formation. However, little is known about how agrin induces the activation of lymphocytes and whose receptors mediate its regulatory effects on these cells. In the present study, agrin was detected in lymphocytes. Up-regulation of agrin expression was involved in lymphocyte activation… CONTINUE READING