Agrin: an extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis.

@article{Cole1996AgrinAE,
  title={Agrin: an extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis.},
  author={Gregory J Cole and Willi Halfter},
  journal={Perspectives on developmental neurobiology},
  year={1996},
  volume={3 4},
  pages={
          359-71
        }
}
Recent studies have documented important roles for heparan sulfate proteoglycans in the control of nervous system development. Agrin is an extracellular matrix protein identified and named based on its involvement in the aggregation of acetylcholine receptors (AChRs) during synaptogenesis at the neuromuscular junction. Recent studies have demonstrated that agrin is a large extracellular heparan sulfate proteoglycan, with a molecular mass in excess of 500 kDa and a protein core of 220 kDa… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 24 CITATIONS

Agrin becomes concentrated at neuroeffector junctions in developing rodent urinary bladder

  • Cell and Tissue Research
  • 2004
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Significance of Heparanase in Cancer and Inflammation

  • Cancer Microenvironment
  • 2011
VIEW 1 EXCERPT
CITES BACKGROUND

Tumorigenic and adhesive properties of heparanase.

  • Seminars in cancer biology
  • 2010
VIEW 1 EXCERPT
CITES BACKGROUND