Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy.

  title={Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy.},
  author={James Charles Grotta and David Chiu and M J Lu and S C Patel and Steven R. Levine and Barbara C Tilley and Thomas G. Brott and E. Clarke Haley and Patrick D. Lyden and Rashmi U. Kothari and Michael Frankel and Christopher A. Lewandowski and R.B. Libman and Thomas Kwiatkowski and Joseph P. Broderick and John R. Marler and J J Corrigan and Stephen J. Huff and Panayiotis D. Mitsias and Sanjay Talati and David Tann{\'e}},
  volume={30 8},
BACKGROUND AND PURPOSE Ischemic changes identified on CT scans performed in the first few hours after stroke onset, which are thought to possibly represent early cytotoxic edema and development of irreversible injury, may have important implications for subsequent treatment. However, insecurity and conflicting data exist over the ability of clinicians to correctly recognize and interpret these changes. We performed a detailed review of selected baseline CT scans from the NINDS rt-PA Stroke… 

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