Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma.

@article{Mssner2002AgonistsOP,
  title={Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma.},
  author={R M{\"o}ssner and Ulrike Schulz and Ullrich Krueger and Peter Middel and Sven Schinner and L{\'a}szl{\'o} F{\"u}zesi and Christine Neumann and K Reich},
  journal={The Journal of investigative dermatology},
  year={2002},
  volume={119 3},
  pages={576-82}
}
Peroxisome proliferator-activated receptor gamma is a member of the nuclear receptor superfamily involved in adipocyte differentiation and glucose homeostasis. There is evidence that peroxisome proliferator-activated receptor gamma may also act as a tumor suppressor. Here, we demonstrate expression of peroxisome proliferator-activated receptor gamma in benign melanocytic naevi, different variants of primary cutaneous melanomas, and melanoma metastases. Peroxisome proliferator-activated receptor… CONTINUE READING
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