Agonists at mu-opioid receptors spin the wheels to keep the action going.

Abstract

A study in this issue of Molecular Pharmacology on agonist-induced internalization of mu-opioid receptors during long-term opiate drug exposure is discussed. The study demonstrates the critical role of re-cycling of reactivated mu receptors back to the plasma membrane for the maintenance of agonist signaling during long-term opiate exposure.

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Cite this paper

@article{Cox2005AgonistsAM, title={Agonists at mu-opioid receptors spin the wheels to keep the action going.}, author={Brian M. Cox}, journal={Molecular pharmacology}, year={2005}, volume={67 1}, pages={12-4} }