Agonistic Properties of Cannabidiol at 5-HT1a Receptors


Cannabidiol (CBD) is a major, biologically active, but psycho-inactive component of cannabis. In this cell culture-based report, CBD is shown to displace the agonist, [3H]8-OH-DPAT from the cloned human 5-HT1a receptor in a concentration-dependent manner. In contrast, the major psychoactive component of cannabis, tetrahydrocannabinol (THC) does not displace… (More)
DOI: 10.1007/s11064-005-6978-1


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@article{Russo2005AgonisticPO, title={Agonistic Properties of Cannabidiol at 5-HT1a Receptors}, author={Ethan B. Russo and Andrea B Burnett and Brian Hall and Keith K. Parker}, journal={Neurochemical Research}, year={2005}, volume={30}, pages={1037-1043} }