Agonist-induced desensitization and endocytosis of heterodimeric GABAB receptors in CHO-K1 cells.

@article{GonzlezMaeso2003AgonistinducedDA,
  title={Agonist-induced desensitization and endocytosis of heterodimeric GABAB receptors in CHO-K1 cells.},
  author={Javier Gonz{\'a}lez-Maeso and Alan Wise and Andrew Green and Jennifer A Koenig},
  journal={European journal of pharmacology},
  year={2003},
  volume={481 1},
  pages={15-23}
}
gamma-Aminobutyric acid B (GABA(B)) receptor is the first discovered G protein-coupled receptor that requires two subunits, GB1 and GB2, to form a functional receptor. Whereas the molecular and functional characteristics of GABA(B) receptors have been recently extensively studied, the mechanisms underlying receptor desensitization and endocytosis are still… CONTINUE READING