Agonist and inverse agonist effects of CL 218872 on benzodiazepine receptors

@article{Gardner1984AgonistAI,
  title={Agonist and inverse agonist effects of CL 218872 on benzodiazepine receptors},
  author={C. Gardner},
  journal={Neuroscience Letters},
  year={1984},
  volume={51},
  pages={1-6}
}
  • C. Gardner
  • Published 1984
  • Biology, Medicine
  • Neuroscience Letters
Extracellular action potentials were recorded from cerebellar Purkinje cells in urethane-anaesthetised rats. Synaptic inhibition was evoked by electrical stimulation of the nearby cortical surface and recorded using peristimulus-time histograms. A benzodiazepine agonist, RU 32007, decreased cell firing rate and increased the inhibitory response duration in parallel. beta-Carboline ethyl ester increased firing and decreased the inhibitory response. In some cases the inhibitory response was… Expand
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References

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