Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors

@article{Egan1998AgonistAO,
  title={Agonist activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors},
  author={C T Egan and Katharine Herrick‐Davis and Keith J. Miller and Richard A Glennon and Milt Teitler},
  journal={Psychopharmacology},
  year={1998},
  volume={136},
  pages={409-414}
}
Abstract Evidence from studies with phenylisopropylamine hallucinogens indicates that the 5HT2A receptor is the likely target for the initiation of events leading to hallucinogenic activity associated with LSD and related drugs. Recently, lisuride (a purported non-hallucinogenic congener of LSD) was reported to be a potent antagonist at the 5HT2C receptor and an agonist at the 5HT2A receptor. LSD exhibited agonist activity at both receptors. These data were interpreted as indicating that the… 

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