Agomelatine and hepatotoxicity: implications of cumulated data derived from spontaneous reports of adverse drug reactions.

@article{Gahr2013AgomelatineAH,
  title={Agomelatine and hepatotoxicity: implications of cumulated data derived from spontaneous reports of adverse drug reactions.},
  author={Maximilian Gahr and Roland Wolfgang Freudenmann and Bernhard J. Connemann and Christoph Hiemke and Carlos Sch{\"o}nfeldt-Lecuona},
  journal={Pharmacopsychiatry},
  year={2013},
  volume={46 6},
  pages={214-20}
}
Considering the antidepressant agomelatine (AGM) there is a discrepancy between the widespread knowledge of the potential of AGM to cause hepatotoxic adverse drug reactions (ADR) and the availability of corresponding published data. This impedes an adequate assessment of the hepatotoxicity profile of AGM. We conducted a query of the database of a German… CONTINUE READING