Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y.

@article{Taksande2011AgmatineIT,
  title={Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y.},
  author={Brijesh Gulabrao Taksande and Nandkishor R Kotagale and Kartik T. Nakhate and Prashant Mali and Dadasaheb M Kokare and Khemraj Hirani and Nishikant K. Subhedar and Chandrabhan Tukaram Chopde and Rajesh Ramesh Ugale},
  journal={British journal of pharmacology},
  year={2011},
  volume={164 2b},
  pages={
          704-18
        }
}
BACKGROUND AND PURPOSE Agmatine, a multifaceted neurotransmitter, is abundantly expressed in the hypothalamic paraventricular nucleus (PVN). Our aim was to assess (i) the effect of agmatine on feeding behaviour and (ii) its association, if any, with neuropeptide Y (NPY). EXPERIMENTAL APPROACH Satiated rats fitted with intra-PVN cannulae were administered agmatine, alone or jointly with (i) α₂-adrenoceptor agonist, clonidine, or antagonist, yohimbine; (ii) NPY, NPY Y₁ receptor agonist, [Leu… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 92 REFERENCES

Similar Papers

Loading similar papers…