Agmatine attenuates lipopolysaccharide induced anorexia and sickness behavior in rats.

Abstract

Sickness behavior is characterized by lethargy, reduced appetite, anhedonia and anxiety. It can be induced in experimental animals by bacterial endotoxin, lipopolysaccharide (LPS). We investigated the impact of intracerebroventricular agmatine injections (5-20μg/rat, icv) on sickness behavior induced by LPS (100μg/rat, ip) in rats. Rats challenged with LPS… (More)
DOI: 10.1016/j.pbb.2015.02.013

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics