Agmatine Modulation of Noradrenergic Neurotransmission in Isolated Rat Blood Vessels.


Agmatine, a vasoactive metabolite of L-arginine, is widely distributed in mammalian tissues including blood vessels. Agmatine binding to imidazoline and α₂-adrenoceptors induces a variety of physiological and pharmacological effects. We investigated the effect of agmatine on contractile responses of the rat pulmonary artery and portal vein induced by… (More)
DOI: 10.4077/CJP.2016.BAE388


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