Aging-related increases in behavioral variability: relations to losses of dopamine D1 receptors.

  title={Aging-related increases in behavioral variability: relations to losses of dopamine D1 receptors.},
  author={Stuart W. S. MacDonald and Sari Karlsson and Anna Rieckmann and Lars Nyberg and Lars B{\"a}ckman},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={32 24},
Intraindividual variability (IIV) reflects within-person changes in performance, such as trial-by-trial fluctuations on a reaction-time (RT) task. The neural underpinnings of IIV remain largely unknown. The neurotransmitter dopamine (DA) is of particular interest here, as human populations that exhibit DA alterations, such as the elderly, attention deficit hyperactivity disorder children, persons with schizophrenia, and Parkinson patients, also show increased behavioral IIV. We examined links… CONTINUE READING
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