Aging neuromodulation impairs associative binding: a neurocomputational account.

@article{Li2005AgingNI,
  title={Aging neuromodulation impairs associative binding: a neurocomputational account.},
  author={Shu-Chen Li and Moshe Naveh-Benjamin and Ulman Lindenberger},
  journal={Psychological science},
  year={2005},
  volume={16 6},
  pages={445-50}
}
Relative to young adults, older adults are particularly impaired in episodic memory tasks requiring associative binding of separate components into compound episodes, such as tasks requiring item-context and item-item binding. This associative-binding deficit has been attributed to senescent changes in frontal-hippocampal circuitry but has not been formally linked to impaired neuromodulation involving this circuitry. Previous neurocomputational work showed that impaired neuromodulation could… CONTINUE READING

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