Aging in the AXC/SSh rat: diminished prostate L-ornithine decarboxylase (ODC) activity reflects diminished prostate ODC protein and transcript content.


Immunotitration of L-ornithine decarboxylase (ODC) activity in ventral prostates of young mature (6-month-old) and aged (26-month-old) AXC/SSh rats established that the relation between enzyme activity and prostate ODC mass content was age invariant, demonstrating that the 4-fold diminution in prostate ODC activity in aged subjects represents decreased ODC… (More)


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