Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?

Abstract

Increased aortic stiffness is an early and independent biomarker of cardiovascular disease. Here we tested the hypothesis that vascular smooth muscle cells (VSMCs) contribute significantly to aortic stiffness and investigated the mechanisms involved. The relative contributions of VSMCs, focal adhesions (FAs), and matrix to stiffness in mouse aorta… (More)
DOI: 10.1152/ajpheart.00392.2014

Topics

7 Figures and Tables

Statistics

02040201520162017
Citations per Year

Citation Velocity: 10

Averaging 10 citations per year over the last 3 years.

Learn more about how we calculate this metric in our FAQ.

Slides referencing similar topics