Aging and muscle: a neuron's perspective.

  title={Aging and muscle: a neuron's perspective.},
  author={Todd M. Manini and Siang Lee Hong and Brian C Clark},
  journal={Current opinion in clinical nutrition and metabolic care},
  volume={16 1},
PURPOSE OF REVIEW Age-related muscle weakness causes a staggering economic, public, and personal burden. Most research has focused on internal muscular mechanisms as the root cause to strength loss. Here, we briefly discuss age-related impairments in the brain and peripheral nerve structures that may theoretically lead to muscle weakness in old age. RECENT FINDINGS Neuronal atrophy in the brain is accompanied by electrical noise tied to declines in dopaminergic neurotransmission that degrades… CONTINUE READING
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