Aging and erectile function

  title={Aging and erectile function},
  author={David R Meldrum and Margaret A. Morris and Joseph C. Gambone and Katherine Esposito},
  journal={The Aging Male},
  pages={1115 - 1124}
Abstract The authors review and discuss numerous factors that influence erectile function and their interactions, based on the published literature. Of critical importance are vascular nitric oxide; nutrition; exercise; weight control and maintaining insulin sensitivity; early treatment of hypertension with attention to effects on erectile function; avoiding sources of oxidative stress such as obesity and smoking; reducing inflammation (e.g. from gingivitis); improving pelvic floor muscle… 
Study on the relationship between sex hormone changes and erectile dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome.
Results showed that PRL can better predict the possibility of ED in CP/CPPS patients than PEDT, and the Prolactin level decreases as the degree of ED increases.
Artificial intelligence based identification of the functional role of hirudin in diabetic erectile dysfunction treatment.
It is found that hirudin, the main active ingredient in the leech, could ameliorate the ED symptoms of the DED mouse model and the underlying mechanism of hirUDin in regulating the activity of MPO was revealed.
A genome-wide association study to identify candidate genes for erectile dysfunction
This study introduced new genes associated with ED, which can be good candidates for further analyzing related to human ED, as well as identified the common cis-regulatory elements of these genes.
Heart aging when near vision difficulty begins
  • Ş. Koç, S. S. Baysal
  • Medicine
    The aging male : the official journal of the International Society for the Study of the Aging Male
  • 2020
As a simple screening test, subjective AA measurement can predict important heart aging parameters, including diastolic dysfunction, as well as near vision deterioration during aging.
Spacing spheroids, curl-up and coiled neuritic plexus of the sacral spinal cord of aged dog: Hypothesis based on continued NADPH diaphorase histological observations
The results suggested that the N-d sensory inputs interrupted and disconnected with integration of autonomic centers and output circuits of regulating urogenital organs during the aging.


A multifaceted approach to maximize erectile function and vascular health.
After production of NO and cyclic GMP are improved, use of phosphodiesterase-5 inhibitors should result in greater success in treating remaining erectile dysfunction and a multifaceted approach will maximize both erectile function and vascular health.
The link between erectile and cardiovascular health: the canary in the coal mine.
By better understanding the complex factors influencing erectile and overall vascular health, physicians can help their patients prevent vascular disease and improve erectile function, which provides more immediate motivation for men to improve their lifestyle habits and cardiovascular health.
Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial.
Lifestyle changes are associated with improvement in sexual function in about one third of obese men with erectile dysfunction at baseline, and changes in body mass index, physical activity, and C-reactive protein were independently associated with changes in IIEF score.
Regular intercourse protects against erectile dysfunction: Tampere Aging Male Urologic Study.
Regular intercourse protects against the development of erectile dysfunction among men aged 55 to 75 years; therefore, doctors should support patients' sexual activity.
Erectile dysfunction associates with endothelial dysfunction and raised proinflammatory cytokine levels in obese men
Erectile and endothelial dysfunction associate in obese men and may contribute to their raised cardiovascular risk through impaired nitric oxide availability elicited by a low-grade inflammatory state.
Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial
Prelox is a promising alternative to treat mild to moderate erectile dysfunction and Intake of Pycnogenol for 1 month restored erectile function to normal.
Epidemiology and risk factors of lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction
The epidemiology and risk factors of the combined phenotype LUTS/BPH – ED are studied, suggesting that patients with BPH or LutS easily develop ED, and that LUTs/B PH symptoms often coexist with ED.
Lifestyle and metabolic approaches to maximizing erectile and vascular health
Lifestyle modifications, including physical and penile-specific exercise, weight loss, omega-3 and folic acid supplements, reduced intakes of fat and sugar, and improved antioxidant status through diet and/or supplements should be integrated into any comprehensive approach to maximizing erectile function, resulting in greater overall success and patient satisfaction.
Effect of periodontitis on erectile function and its possible mechanism.
The function of penile erection is impaired byperiodontitis and the decreased in the expression of eNOS and NOS activity in penile cavernous tissue caused by mild systemic inflammatory status in periodontitis may be one of the important risk factors of ED.
Mediterranean diet improves erectile function in subjects with the metabolic syndrome
A Mediterranean-style diet rich in whole grain, fruits, vegetables, legumes, walnut, and olive oil might be effective per se in reducing the prevalence of ED in men with the metabolic syndrome.