Aging and endothelial progenitor cell telomere length in healthy men.

@article{Kushner2009AgingAE,
  title={Aging and endothelial progenitor cell telomere length in healthy men.},
  author={Erich James Kushner and Gary P. Van Guilder and Owen J Maceneaney and Jennifer Nell Cech and Brian L Stauffer and Christopher A DeSouza},
  journal={Clinical chemistry and laboratory medicine},
  year={2009},
  volume={47 1},
  pages={
          47-50
        }
}
BACKGROUND Telomere length declines with age in mature endothelial cells and is thought to contribute to endothelial dysfunction and atherogenesis. Bone marrow-derived circulating endothelial progenitor cells (EPCs) are critical to vascular health as they contribute to both reendothelialization and neovascularization. We tested the hypothesis that EPC telomere length decreases with age in healthy adult humans. METHODS Peripheral blood samples were collected from 40 healthy, non-obese… CONTINUE READING
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