Aging Specifically Impairs amnesiac-Dependent Memory in Drosophila

@article{Tamura2003AgingSI,
  title={Aging Specifically Impairs amnesiac-Dependent Memory in Drosophila},
  author={Takuya Tamura and A. M. Chiang and Naomi Ito and H T Liu and Junjiro Horiuchi and Tim Tully and Minoru Saitoe},
  journal={Neuron},
  year={2003},
  volume={40},
  pages={1003-1011}
}
Age-related memory impairment (AMI) is observed in many species. However, it is uncertain whether AMI results from a specific or a nonspecific decay in memory processing. In Drosophila, memory acquired after a single olfactory conditioning paradigm has three distinct phases: short-term memory (STM), middle-term memory (MTM), and longer-lasting anesthesia-resistant memory (ARM). Here, we demonstrate that age-related defects in olfactory memory are identical to those of the MTM mutant amnesiac… CONTINUE READING
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Making connections between developmental and behavioral plasticity in Drosophila

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