Aging: impact upon local cerebral oxygenation and blood flow with acute isovolemic hemodilution.

@article{Li2006AgingIU,
  title={Aging: impact upon local cerebral oxygenation and blood flow with acute isovolemic hemodilution.},
  author={Min Li and Sarah J. Ratcliffe and Frank Knoll and Jiusheng Wu and Beau M. Ances and Waseem Mardini and Thomas F. Floyd},
  journal={Journal of neurosurgical anesthesiology},
  year={2006},
  volume={18 2},
  pages={125-31}
}
Data from the neurosurgical critical care arena demonstrate a correlation between cerebral oxygenation, survival, and cognitive function. Transfusion may increase and hemodilution decrease cerebral oxygenation. Both acute and chronic anemia have been associated with cognitive dysfunction. Aggressive blood conservation protocols have been instituted across all age groups without conclusive evidence for their impact upon outcome. Aged subjects are at the greatest risk of cognitive sequelae after… CONTINUE READING