Aging: Drugs to Eliminate Methylglyoxal, a Reactive Glucose Metabolite, and Advanced Glycation Endproducts

  title={Aging: Drugs to Eliminate Methylglyoxal, a Reactive Glucose Metabolite, and Advanced Glycation Endproducts},
  author={Indu Dhar and Kaushik Desai},
The aging process not only affects the whole body, but also affects individual cells. While the age-related changes in the body are popularly recognized as wrinkling of the skin, indicating alterations in basement membrane proteins, the processes of cellular aging are less well defined. The underlying common theme of cellular aging and whole body aging seems to be an increase in oxidative stress. Advanced glycation endproducts (AGEs), which are widely accepted to alter basement membrane… 

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