Aging, lipofuscin formation, and free radical-mediated inhibition of cellular proteolytic systems

@article{Szweda2003AgingLF,
  title={Aging, lipofuscin formation, and free radical-mediated inhibition of cellular proteolytic systems},
  author={Pamela A Szweda and Melissa M Camouse and Kathleen Corrigan Lundberg and Terry D. Oberley and Luke I. Szweda},
  journal={Ageing Research Reviews},
  year={2003},
  volume={2},
  pages={383-405}
}
Alterations in a wide array of physiological functions are a normal consequence of aging. Importantly, aged individuals exhibit an enhanced susceptibility to various degenerative diseases and appear less able than their young and adult counterparts to withstand (patho)physiological stress. Elucidation of mechanisms at play in the aging process would benefit the development of effective strategies for enhancing the quality of life for the elderly. It is likely that decrements in cellular and… CONTINUE READING

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