Aging, exercise, and muscle protein metabolism.

  title={Aging, exercise, and muscle protein metabolism.},
  author={Ren{\'e} Koopman and Luc Jc van Loon},
  journal={Journal of applied physiology},
  volume={106 6},
Aging is accompanied by a progressive loss of skeletal muscle mass and strength, leading to the loss of functional capacity and an increased risk of developing chronic metabolic disease. The age-related loss of skeletal muscle mass is attributed to a disruption in the regulation of skeletal muscle protein turnover, resulting in an imbalance between muscle protein synthesis and degradation. As basal (fasting) muscle protein synthesis rates do not seem to differ substantially between the young… CONTINUE READING
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