Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart.

@article{Olivetti1996AgingCH,
  title={Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart.},
  author={Giorgio Olivetti and E Cigola and Roberta Maestri and Domenico Corradi and Costanza Anna Maria Lagrasta and Steven R. Gambert and Piero Anversa},
  journal={Journal of molecular and cellular cardiology},
  year={1996},
  volume={28 7},
  pages={1463-77}
}
The current investigation was designed to evaluate whether the proportion of mononucleated binucleated, trinucleated and tetranucleated myocytes varies in the left ventricle, interventricular septum and right ventricular free wall with aging, cardiac hypertrophy and ischemic cardiomyopathy. In addition, the number and dimensional properties of myocytes were measured to determine whether a relationship existed between myocyte size and number, and organ hypertrophy. For this purpose, 72 normal… CONTINUE READING