Aggressive natural killer cell leukemia in an adult with establishment of an NK cell line.

@article{Fernandez1986AggressiveNK,
  title={Aggressive natural killer cell leukemia in an adult with establishment of an NK cell line.},
  author={Louis A V Fernandez and Bucky Pope and C Lee and Ekram Zayed},
  journal={Blood},
  year={1986},
  volume={67 4},
  pages={925-30}
}
There have been many reports of cases in which chronic increases in the numbers of natural killer (NK) cells have been reported. Whether this is reactive or neoplastic in nature has been debated. We report the first case of an aggressive NK cell leukemia in an adult with establishment of an NK cell line. A 70-year-old man had two spontaneous episodes of jejunal perforation and one month later developed a severe febrile illness with moderate splenomegaly. Hemoglobin was 13.1 g/L, and WBC count… CONTINUE READING