Aggressive multimodality therapy for malignant pleural mesothelioma.

  title={Aggressive multimodality therapy for malignant pleural mesothelioma.},
  author={Thomas William Rice and David Adelstein and Thomas Kirby and M G Saltarelli and S. Ramachandra Murthy and M A Van Kirk and Herbert P. Wiedemann and James K. Weick},
  journal={The Annals of thoracic surgery},
  volume={58 1},
Nineteen patients with clinical stage I malignant pleural mesothelioma were treated with aggressive multimodality therapy. Nine patients underwent pleurectomy and decortication followed by immediate intrapleural chemotherapy with cisplatin and mitomycin C. Ten patients required pleuropneumonectomy followed within 1 week to 2 weeks by intrapleural administration of cisplatin (100 mg). Four to 8 weeks after operation, 15 patients underwent postoperative adjuvant cisplatin-based systemic… CONTINUE READING


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