Aggressive CD5-positive B-cell lymphoma after remission of CD5-negative follicular lymphoma with distinct immunoglobulin heavy chain rearrangement and translocation.

Abstract

We report a unique, aggressive B-cell lymphoma that developed after the long-term remission of follicular lymphoma (FL). FL cells were negative for CD5, whereas aggressive lymphoma cells were positive for CD5. In FL, one immunoglobulin heavy chain gene (IGH) allele underwent V/D/J recombination and another t(14;18)(q32;q21). In aggressive lymphoma, one IGH… (More)
DOI: 10.1007/s12185-008-0160-x

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@article{Sonoki2008AggressiveCB, title={Aggressive CD5-positive B-cell lymphoma after remission of CD5-negative follicular lymphoma with distinct immunoglobulin heavy chain rearrangement and translocation.}, author={Takashi Sonoki and Sonoko Ishihara and Shima Uneda and Nobuyoshi Hanaoka and Miwa Kurimoto and Hiroshi Matsuoka and Hideki Nakakuma}, journal={International journal of hematology}, year={2008}, volume={88 3}, pages={299-303} }