Aggregations of granule cells in the basal forebrain (islands of Calleja): Golgi and cytoarchitectonic study in different mammals, including man

  title={Aggregations of granule cells in the basal forebrain (islands of Calleja): Golgi and cytoarchitectonic study in different mammals, including man},
  author={Gundela Meyer and Tom{\'a}s Gonz{\'a}lez-Hern{\'a}ndez and Francisco Javier Carrillo-Padilla and Romualdo Ferres-Torres},
  journal={Journal of Comparative Neurology},
The granule cell islands in the olfactory tubercle (islands of Calleja) and the insula magna of Calleja are present in all species examined in this study: cat, rat, mouse, rabbit, hedgehog, monkey, man, and dolphin, displaying the same basic morphology. They appear as rather undifferentiated neurons with a poorly developed dendritic tree and a short unramified axon that does not leave the island. The larger islands and the insula magna are associated with medium‐sized neurons often lying in… 

Development of the Islands of Calleja

Cell structure in the islands of calleja in carnivore brains

The aim of the present work was to study the structural and ultrastructural characteristics of all types of nerve cells present in the islands of Calleja in carnivores and to detect the presence of some of their presumed projections (to the posterolateral hypothalamus).

Laminar and spatial localization of the islands of Calleja in mice

Basal telencephalic regions connected with the olfactory bulb in a Madagascan hedgehog tenrec

The variability of cell populations and olfactory bulb connections shown here may help to clarify both phylogenetic relationships and the significance of individual basal telencephalic subdivisions.

The paleocortical ventricle is the origin of reelin‐expressing neurons in the marginal zone of the foetal human neocortex

The results show that the paleocortical ventricle gives rise to a stream of neurons which extends over the cortical MZ as the subpial granular layer, and the fact that SGL derivatives express reelin suggests that this transient cell layer may play a significant role in the establishment of the complex cytoarchitecture of the cerebral cortex.

Ventral striatal Islands of Calleja neurons control grooming in mice

It is shown that optogenetic activation of OT D3 neurons robustly initiates self-grooming in mice while suppressing other ongoing behaviors, and has important implications for the neural control of grooming.

Thg‐1pit gene expression in granule cells of the developing mouse brain and in their synaptic targets, mature Purkinje, and mitral cells

It is concluded that Thg‐1pit is relevant to specification, proliferation/migration, differentiation, and mature function of granule/interneuron cells in different brain districts, as well as to the function of mature, but not immature, Purkinje cells and mitral cells.

Corridors of Migrating Neurons in Human Brain and Their Decline during Infancy

It is found that the infant human subventricular zone and RMS contain an extensive corridor of migrating immature neurons before 18 months of age but, contrary to previous reports, this germinal activity subsides in older children and is nearly extinct by adulthood.



Granule cells of the olfactory tubercle and the question of the islands of calleja

The granule cell clusters in the rat olfactory tubercle were studied in Nissl‐stained and Golgi‐impregnated sections and revealed a small population of granule cells is spine‐rich, which may contain larger neurons.

The islands of calleja: Organization and connections

Observations indicate that the islands of Calleja constitute a unique population of granule cells, located in the olfactory tubercle, innervated by dopamine neurons of the mesencephalon and interconnected with Olfactory and non‐olfactory components of the basal forebrain.

Cell configurations in the olfactory tubercle of the rat

The rat olfactory tubercle was studied with the rapid Golgi method. Several distinct cell types were identified mainly on the basis of the size of their somata and the structure of their dendrites.

The island of Calleja complex of rat basal forebrain. I. Light and electron microscopic observations

An analysis of the cells and their processes within the island of Calleja complexes (ICC) was made in light and electron microscopic preparations to determine synaptic relationships within this part

Olfactory structures of the forebrain in the reeler mutant mouse

The view that the relationship of pyramidal cell to complex, external plexiform layer is the cardinal geometric principle defining a normal cortex is adopted, and it is suggested that derangement of this relationship may be the common denominator in the reeler cortical phenotype.

Golgi studies on the development of granule cells of the rat olfactory bulb with reference to migration in the subependymal layer

  • K. Kishi
  • Biology
    The Journal of comparative neurology
  • 1987
The morphology and the development of the cells in the subependymal layer and of granule cells of the olfactory bulb were examined by Nissl and Golgi staining in postnatal rats to identify bipolar cells and relatively large cells with many cytoplasmic processes considered to belong to the glial cell line.

The ventral striatopallidothalamic projection: I. The striatopallidal link originating in the striatal parts of the olfactory tubercle

The main and apparently only significant termination from the striatal cells in the olfactory tubercle is located immediately deep to the dense cell layer in areas that could be identified as part of the ventral pallidum on the basis of either the Nissl method or glutamate decarboxylase immunocytochemistry.

Autoradiographic study of histogenesis in the mouse olfactory bulb I. Time of origin of neurons and neuroglia

  • J. Hinds
  • Biology
    The Journal of comparative neurology
  • 1968
The results support the concept that some germinal layers of the central nervous system are programmed to produce a succession of cell types, larger cells before smaller ones, as in the olfactory formation.