Aggregation and G-quadruplex DNA-binding study of 6a,12a-diazadibenzo-[a,g]fluorenylium derivative.

Abstract

The aggregation and DNA binding behavior of a new G-quadruplex selective ligand, 6a,12a-diazadibenzo-[a,g]fluorenylium derivative, was studied by UV-vis absorption and fluorescence spectroscopy. The formation of ligand aggregates with different spectral characteristics was observed at low and high concentration of NaCl, respectively. The ligand binds to G… (More)

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@article{Juskowiak2004AggregationAG, title={Aggregation and G-quadruplex DNA-binding study of 6a,12a-diazadibenzo-[a,g]fluorenylium derivative.}, author={Bernard Juskowiak and Elzbieta Galezowska and Natalia Koczorowska and Tadeusz Władysław Hermann}, journal={Bioorganic & medicinal chemistry letters}, year={2004}, volume={14 14}, pages={3627-30} }