Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure.

Abstract

Robust computational approaches are needed to characterize systems-level responses to chemical perturbations in environmental and clinical toxicology applications. Appropriate characterization of response presents a methodological challenge when dealing with diverse phenotypic endpoints measured using in vivo systems. In this article, we propose an… (More)
DOI: 10.1016/j.reprotox.2016.04.012

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