Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease.

@article{Bangen2015AggregateEO,
  title={Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease.},
  author={Katherine J. Bangen and Daniel A. Nation and Lisa Delano-Wood and Gali H. Weissberger and Lawrence Arthur Hansen and Douglas R. Galasko and David P. Salmon and Mark W. Bondi},
  journal={Alzheimer's & dementia : the journal of the Alzheimer's Association},
  year={2015},
  volume={11 4},
  pages={394-403.e1}
}
We examined the relationships of antemortem vascular risk factors to postmortem cerebrovascular and Alzheimer's disease (AD) pathologies. Eighty-four AD patients underwent an assessment of vascular risk (blood pressure, cholesterol, smoking, cardiovascular disease, diabetes, atrial fibrillation, transient ischemic attack [TIA], or stroke) and later underwent brain autopsy. Given our aim to examine mild cerebrovascular changes (CVCs), individuals were excluded if autopsy revealed large stroke… CONTINUE READING
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