Aggregate complexes of HIV-1 induced by multimeric antibodies

Abstract

Antibody mediated viral aggregation may impede viral transfer across mucosal surfaces by hindering viral movement in mucus, preventing transcytosis, or reducing inter-cellular penetration of epithelia thereby limiting access to susceptible mucosal CD4 T cells and dendritic cells. These functions may work together to provide effective immune exclusion of… (More)
DOI: 10.1186/s12977-014-0078-8

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