Agglutination of isolated platelet membranes.

  title={Agglutination of isolated platelet membranes.},
  author={Meinrad Gawaz and Ilka Ott and Armin J. Reininger and Ulrich Heinzmann and F. J. Neumann},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={16 5},
Platelet membrane glycoproteins play a central role in platelet aggregation and thus in primary hemostasis. To investigate mechanisms of platelet-platelet interaction in the absence of cellular activation events, we studied immunological and functional aspects of isolated platelet membranes. Platelet membranes contained significant amounts of the inducible fibrinogen receptor, glycoprotein (GP) IIb-IIIa, which exposes conformation-dependent LIBS1 and PMI-1 epitopes in response to fibrinogen… CONTINUE READING