Agents that induce pseudo-allergic reaction.

  title={Agents that induce pseudo-allergic reaction.},
  author={H S Wang and H S Wang and Z P Liu},
  journal={Drug discoveries \& therapeutics},
  volume={5 5},
Pseudo-allergic reactions may result from the activation of inflammatory or anaphylactic mechanisms independent of antigen-specific immune responses. [] Key Method The agents discussed here are divided into three types: (i) Direct mast cell activators, which may activate mast cells in an IgE-independent manner, such as opioid drugs, basic secretagogues and calcium ionophore A23187; (ii) Complement activators, including liposomes, radiocontrast media and Cremophor EL, which may activate the complement system…

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