Agents that affect cAMP levels or protein kinase A activity modulate memory consolidation when injected into rat hippocampus but not amygdala.

@article{Bevilaqua1997AgentsTA,
  title={Agents that affect cAMP levels or protein kinase A activity modulate memory consolidation when injected into rat hippocampus but not amygdala.},
  author={L{\'i}a R. M. Bevilaqua and Patr{\'i}cia Grolli Ardenghi and Nadja Schr{\"o}der and Elke Bromberg and Jo{\~a}o Quevedo and P K Schmitz and Marisa Bianchin and Roger Walz and Eric Schaeffer and Jorge Horacio Medina and Ivan A. Izquierdo},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={1997},
  volume={30 8},
  pages={967-70}
}
Male Wistar rats were trained in one-trial step-down inhibitory avoidance using a 0.4-mA footshock. At various times after training (0, 1.5, 3, 6 and 9 h for the animals implanted into the CA1 region of the hippocampus; 0 and 3 h for those implanted into the amygdala), these animals received microinfusions of SKF38393 (7.5 micrograms/side), SCH23390 (0.5 microgram/side), norepinephrine (0.3 microgram/side), timolol (0.3 microgram/side), 8-OH-DPAT (2.5 micrograms/side), NAN-190 (2.5 micrograms… CONTINUE READING

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