Agent-based computational model investigates muscle-specific responses to disuse-induced atrophy.

Abstract

Skeletal muscle is highly responsive to use. In particular, muscle atrophy attributable to decreased activity is a common problem among the elderly and injured/immobile. However, each muscle does not respond the same way. We developed an agent-based model that generates a tissue-level skeletal muscle response to disuse/immobilization. The model incorporates… (More)
DOI: 10.1152/japplphysiol.01150.2014

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