Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans.

@article{Houthoofd2002AgeingIR,
  title={Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans.},
  author={Koen Houthoofd and Bart P. Braeckman and Isabelle Lenaerts and Kristel Brys and Annemie De Vreese and Sylvie Van Eygen and Jacques R. Vanfleteren},
  journal={Experimental gerontology},
  year={2002},
  volume={37 8-9},
  pages={1015-21}
}
The nematode Caenorhabditis elegans responds to unfavourable environmental conditions by arresting development and entering diapause as a dauer larva. Dauers can survive several times the normal life span and the duration of the dauer state has no effect on postdauer life span. This led to the suggestion that dauers are non-ageing, and that dauers eventually perish as the consequence of depletion of stored nutrients. We have investigated physiological changes associated with long-term diapause… CONTINUE READING