Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

@inproceedings{Partridge2011AgeingID,
  title={Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network},
  author={Linda Partridge and Nazif Alic and Ivana Bjedov and Matt D.W. Piper},
  booktitle={Experimental Gerontology},
  year={2011}
}
A remarkable discovery of recent years is that, despite the complexity of ageing, simple genetic interventions can increase lifespan and improve health during ageing in laboratory animals. The pathways involved have often proved to sense nutrients and to match costly activities of organisms, such as growth, metabolism and reproduction, to nutrient status. For instance, the insulin/insulin-like growth factor and Target of Rapamycin signalling network has proved to play a function in ageing, from… CONTINUE READING