Ageing human bone: factors affecting its biomechanical properties and the role of collagen.

@article{Zioupos2001AgeingHB,
  title={Ageing human bone: factors affecting its biomechanical properties and the role of collagen.},
  author={Peter Zioupos},
  journal={Journal of biomaterials applications},
  year={2001},
  volume={15 3},
  pages={187-229}
}
  • Peter Zioupos
  • Published 2001 in Journal of biomaterials applications
The incidence of fractures increases with age. This is partly due to extraosseous factors and partly to the increased fragility of the bone material itself. Ageing adversely affects the "quality" of human bone material, its elastic and ultimate properties. The hypothesis here is that these effects are caused by factors such as architectural changes, compositional changes, physicochemical changes, changes at the micromechanical level, and the degree of prior in vivo microdamage. Examination of… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2015
View 1 Excerpt

Similar Papers

Loading similar papers…