Ageing and myeloid-derived suppressor cells: possible involvement in immunosenescence and age-related disease

@article{Bueno2014AgeingAM,
  title={Ageing and myeloid-derived suppressor cells: possible involvement in immunosenescence and age-related disease},
  author={Valqu{\'i}ria Bueno and Osvaldo Augusto Sant’anna and Janet M. Lord},
  journal={AGE},
  year={2014},
  volume={36},
  pages={1-12}
}
Infections, cancer and autoimmune diseases occur more frequently in the elderly, and although many factors contribute to this, the age-related remodelling of the immune system, termed immunosenescence, plays a major role. Over the last two decades, studies have evaluated the effect of ageing on both the adaptive and innate arms of the immune system and demonstrated compromised function in several cells including lymphocytes (naïve, effector and memory), regulatory T and B cells, monocytes… CONTINUE READING
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