Ageing, Serotonin and Ketanserin

In both acute and long term clinical studies, the antihypertensive effects of the S2-serotonergic receptor antagonist ketanserin are more marked in the elderly than in younger patients. The acute effect of ketanserin 10mg intravenously was studied in 57 patients between 25 and 90 years and a significant negative correlation was shown between age and the… CONTINUE READING