Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom.

@article{Pebody2013AgespecificVE,
  title={Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom.},
  author={Richard G Pebody and Nick J. Andrews and Douglas M. Fleming and J. Mcmenamin and Simon Cottrell and Brian P. Smyth and Hayley Durnall and Chris Robertson and Wj Carman and Jen Ellis and P Sebastian-Pillai and Maria Zambon and Cheryl Kearns and Catherine H. Moore and Daniel Rh Thomas and J M Watson},
  journal={Epidemiology and infection},
  year={2013},
  volume={141 3},
  pages={
          620-30
        }
}
An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010. The test-negative case-control study design was employed based on patients consulting primary care. Overall TIV effectiveness, adjusted for age and month, against confirmed influenza A(H1N1)pdm 2009 infection was 56% (95% CI 42-66); age-specific adjusted VE was 87% (95% CI 45-97) in <5… CONTINUE READING

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