Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry.

@article{Haring2012AgespecificRR,
  title={Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry.},
  author={Robin Haring and Anke Hannemann and U. John and D{\"o}rte Radke and Matthias Nauck and Henri Wallaschofski and Laura H Owen and Jo Adaway and Brian G Keevil and Georg Brabant},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 2},
  pages={408-15}
}
OBJECTIVE RIA-based sex hormone measurements offer only limited precision and specificity in the low concentration range of women. Therefore, we aimed to establish age-specific reference ranges for serum sex hormone concentrations in women using mass spectrometry and quantile regression. METHODS AND RESULTS Data from 985 women aged 20-80 yr, recruited for the prospective Study of Health in Pomerania, were included in the analyses. Quantile regressions models were performed to calculate the… CONTINUE READING
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