Age-related vascular stiffening: causes and consequences

@inproceedings{Kohn2015AgerelatedVS,
  title={Age-related vascular stiffening: causes and consequences},
  author={Julie C. Kohn and Marsha C Lampi and Cynthia A. Reinhart-King},
  booktitle={Front. Genet.},
  year={2015}
}
Arterial stiffening occurs with age and is closely associated with the progression of cardiovascular disease. Stiffening is most often studied at the level of the whole vessel because increased stiffness of the large arteries can impose increased strain on the heart leading to heart failure. Interestingly, however, recent evidence suggests that the impact of increased vessel stiffening extends beyond the tissue scale and can also have deleterious microscale effects on cellular function. Altered… CONTINUE READING
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