Age-related thermoregulatory differences during core cooling in humans.

  title={Age-related thermoregulatory differences during core cooling in humans.},
  author={Steven M. Frank and Srinivasa N. Raja and Christian F. Bulcao and David S. Goldstein},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  volume={279 1},
  • S. FrankS. Raja D. Goldstein
  • Published 1 July 2000
  • Medicine
  • American journal of physiology. Regulatory, integrative and comparative physiology
The current study assessed sympathetic neuronal and vasomotor responses, total body oxygen consumption, and sensory thermal perception to identify thermoregulatory differences in younger and older human subjects during core cooling. Cold fluid (40 ml/kg, 4 degrees C) was given intravenously over 30 min to decrease core temperature (Tc) in eight younger (age 18-23) and eight older (age 55-71) individuals. Compared with younger subjects, the older subjects had significantly lower Tc thresholds… 

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