Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals.

  title={Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals.},
  author={Kevin E Yarasheski and Rebecca Scherzer and Donald Philip Kotler and Adrian Dobs and Phyllis C. Tien and Cora E. Lewis and Richard A. Kronmal and Steven B. Heymsfield and Peter Bacchetti and Carl Grunfeld},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  volume={66 3},
BACKGROUND Skeletal muscle (SM) mass decreases with advanced age and with disease in HIV infection. It is unknown whether age-related muscle loss is accelerated in the current era of antiretroviral therapy and which factors might contribute to muscle loss among HIV-infected adults. We hypothesized that muscle mass would be lower and decline faster in HIV-infected adults than in similar-aged controls. METHODS Whole-body (1)H-magnetic resonance imaging was used to quantify regional and total SM… CONTINUE READING
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