Age-related retinal function changes in albino and pigmented rats.

  title={Age-related retinal function changes in albino and pigmented rats.},
  author={Jason Charng and Christine T. O. Nguyen and Bang V. Bui and Algis Jonas Vingrys},
  journal={Investigative ophthalmology & visual science},
  volume={52 12},
PURPOSE To investigate the effect of old age (3 vs. 18 months) on the retinal function of albino (Sprague-Dawley [SD]) and pigmented (Long-Evans [LE]) rats. METHODS Electroretinograms (ERG) were recorded in both albino (SD; 3 months old n = 16, 18 months old n = 16) and pigmented (LE; 3 months n = 16, 18 months n = 5) rats. Data are analyzed for photoreceptor, ON-bipolar, and retinal ganglion cell (RCG) amplitudes as well as photoreceptor and ON-bipolar cell sensitivities. RESULTS In the… CONTINUE READING


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